10.4125/PD0012TH
Wu, Ming-Yu
Ming-Yu
Wu
Li, Kun
Kun
Li
Wang, Na
Na
Wang
He, Ting
Ting
He
Yu, Xiao-Qi
Xiao-Qi
Yu
A Novel Catalyst-Free
Tandem Reaction for the Synthesis of 5-Hydroxy-1,5-dihydro-2H-pyrrol-2-ones in Water Medium
Georg Thieme Verlag, Stuttgart, New York
2011
PrimaryData
Chemistry
2011-05-26
2011
en
10.1055/s-0030-1260049
121856 Bytes
A novel catalyst-free, water-medium, tandem reaction for the
synthesis of 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones
was developed through a one-pot strategy from nitroethylenes and
1,3-dicarbonyl compounds. A series of 1-aryl-2-nitroethenes and
1-nitroalk-1-enes were surveyed to determine the scope of this tandem reaction
with moderate to good yield.