TY - RPRT
T1 - Two new linear acetogenins from the fruits of Goniothalamus gracilipes
AU - Trieu, Quy Hung
AU - Mai, Huong Doan Thi
AU - Litaudon, Marc
AU - Thi, Dao Phi
AU - Tran, Tuan Anh
AU - Nguyen, Van Hung
AU - Chau, Van Minh
AU - Pham, Van Cuong
DO - 10.6084/M9.FIGSHARE.5212558
UR - https://tandf.figshare.com/articles/journal_contribution/Two_new_linear_acetogenins_from_the_fruits_of_i_Goniothalamus_gracilipes_i_/5212558/1
AB - Two new linear acetogenins, gracilipin A (1) and methylsaccopetrin A (2) along with seven known compounds, saccopetrin A (3), 7,3′,4′-trimethylquercetin (4), rhamnazin (5), casticin (6), isokanugin (7), melisimplexin (8) and 5-hydroxy-3,7-dimethoxy-3′,4′-methylenedioxyflavone (9) were isolated from the fruits of Goniothalamus gracilipes Bân. Their structures were established by spectral analysis, such as mass spectrometry, 1D-NMR, 2D-NMR and circular dichroism (CD). Compounds 1 and 3 showed cytotoxic activity against KB cell line with IC50 values of 14.6 and 15.3 μM, respectively.
KW - Biophysics
KW - Biochemistry
KW - Microbiology
KW - FOS: Biological sciences
KW - FOS: Biological sciences
KW - Genetics
KW - Pharmacology
KW - Biotechnology
KW - 59999 Environmental Sciences not elsewhere classified
KW - FOS: Earth and related environmental sciences
KW - FOS: Earth and related environmental sciences
KW - 39999 Chemical Sciences not elsewhere classified
KW - FOS: Chemical sciences
KW - FOS: Chemical sciences
KW - Ecology
KW - 69999 Biological Sciences not elsewhere classified
KW - Developmental Biology
KW - Inorganic Chemistry
KW - Hematology
KW - Plant Biology
KW - 60506 Virology
PY - 2017
PB - Taylor & Francis
ER -