TY - RPRT T1 - Two new linear acetogenins from the fruits of Goniothalamus gracilipes AU - Trieu, Quy Hung AU - Mai, Huong Doan Thi AU - Litaudon, Marc AU - Thi, Dao Phi AU - Tran, Tuan Anh AU - Nguyen, Van Hung AU - Chau, Van Minh AU - Pham, Van Cuong DO - 10.6084/M9.FIGSHARE.5212558 UR - https://tandf.figshare.com/articles/journal_contribution/Two_new_linear_acetogenins_from_the_fruits_of_i_Goniothalamus_gracilipes_i_/5212558/1 AB - Two new linear acetogenins, gracilipin A (1) and methylsaccopetrin A (2) along with seven known compounds, saccopetrin A (3), 7,3′,4′-trimethylquercetin (4), rhamnazin (5), casticin (6), isokanugin (7), melisimplexin (8) and 5-hydroxy-3,7-dimethoxy-3′,4′-methylenedioxyflavone (9) were isolated from the fruits of Goniothalamus gracilipes Bân. Their structures were established by spectral analysis, such as mass spectrometry, 1D-NMR, 2D-NMR and circular dichroism (CD). Compounds 1 and 3 showed cytotoxic activity against KB cell line with IC50 values of 14.6 and 15.3 μM, respectively. KW - Biophysics KW - Biochemistry KW - Microbiology KW - FOS: Biological sciences KW - FOS: Biological sciences KW - Genetics KW - Pharmacology KW - Biotechnology KW - 59999 Environmental Sciences not elsewhere classified KW - FOS: Earth and related environmental sciences KW - FOS: Earth and related environmental sciences KW - 39999 Chemical Sciences not elsewhere classified KW - FOS: Chemical sciences KW - FOS: Chemical sciences KW - Ecology KW - 69999 Biological Sciences not elsewhere classified KW - Developmental Biology KW - Inorganic Chemistry KW - Hematology KW - Plant Biology KW - 60506 Virology PY - 2017 PB - Taylor & Francis ER -